Week 5 NFL picks, odds, 2022 best bets from advanced model: This 5-way football parlay pays 25-1

For the second straight week, the NFL travels overseas as the New York Giants take,

 on the Green Bay Packers in London during the Week 5 NFL schedule. New York (3-1) won both of its previous regular-season games in England,

 including a 13-10 triumph over Miami at Wembley Stadium in the first international game in league history in 2007.

 Green Bay (3-1), which is seeking its fourth straight victory after opening the 2022 season with a loss at Minnesota,

 will play outside the United States for the first time. The Packers are 8-point favorites in the latest Week 5 NFL odds at Caesars Sportsbook

. Which Week 5 NFL lines should you target with your Week 5 NFL bets? Before you make any Week 5 NFL picks or NFL parlays,

 be sure to see the NFL predictions and betting advice from SportsLine's proven computer model.

The model, which simulates every NFL game 10,000 times,

 is up almost $7,000 for $100 players on top-rated NFL picks since its inception.

The model, which simulates every NFL game 10,000 times,

The model enters Week 5 of the 2022 NFL season on an incredible 139-103 run on top-rated NFL picks that dates back to the 2017 season.  

The model also ranked in the top 10 on NFLPickWatch four

 Football Pick'em players four times during that span. Anyone who has followed it is way up.

of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports

Next story

No. 16 BYU at Notre Dame Odds, Prediction for Week 6