Matt Rhule finished last season on the hot seat for the Carolina Panthers,
and he was removed from it when he was fired following the Panthers' 37-15 loss to San Francisco last Sunday.
While a midseason coaching change doesn't portend a strong finish for Carolina, it creates a murky situation for the
Los Angeles Rams when it comes to making Week 6 NFL predictions. The Rams are just 1-4 this season against the
spread and are the biggest favorites (-10.5) in the Week 6 NFL odds at Caesars Sportsbook. The double-digit line is one of the largest NFL spreads we'll see all season.
The Rams were the latest victim of the Cooper Rush-led Cowboys in Week 5 as 5.5-point home favorites,
but just need to win against Carolina this week to go into their bye at 3-3 straight-up this season
. All of the Week 6 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL
The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL
picks since its inception. The model enters Week 6 of the 2022 NFL season on an incredible 146-106 run on top-rated NFL picks that dates back to the 2017 season.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and
beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.
Top Week 6 NFL predictions One of the model's strongest Week 6 NFL picks is that the Giants (+6) cover the spread at home against the Ravens.
Top Week 6 NFL predictions New York is one of the most surprising teams this season with 4-1 records overall and against the spread.